{"id":702,"date":"2026-06-10T03:25:19","date_gmt":"2026-06-09T19:25:19","guid":{"rendered":"https:\/\/npi-disruptors.com\/?page_id=702"},"modified":"2026-07-23T04:27:30","modified_gmt":"2026-07-22T20:27:30","slug":"elementor-702","status":"publish","type":"page","link":"https:\/\/npi-disruptors.com\/","title":{"rendered":"Home"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"702\" class=\"elementor elementor-702\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6931ca0 e-flex e-con-boxed e-con e-parent\" data-id=\"6931ca0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-df9d6f7 elementor-widget elementor-widget-html\" data-id=\"df9d6f7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<form role=\"search\" method=\"get\" action=\"\/\" class=\"npi-search-form\">\r\n\r\n    <select name=\"npi_search_type\" class=\"npi-search-type\">\r\n        <option value=\"all\">All<\/option>\r\n        <option value=\"compound\">Small Molecules<\/option>\r\n        <option value=\"protein\">Proteins<\/option>\r\n    <\/select>\r\n\r\n    <input\r\n        type=\"search\"\r\n        name=\"s\"\r\n        class=\"npi-search-input\"\r\n        placeholder=\"Type to start searching...\"\r\n        required\r\n    >\r\n\r\n    <button type=\"submit\" class=\"npi-search-button\">\r\n        Search\r\n    <\/button>\r\n\r\n<\/form>\r\n\r\n<style>\r\n.npi-search-form {\r\n    display: flex;\r\n    width: 100%;\r\n    max-width: 900px;\r\n    margin: 0 auto;\r\n}\r\n\r\n.npi-search-type {\r\n    width: 180px;\r\n    padding: 14px;\r\n    border: 1px solid #ccc;\r\n    border-right: none;\r\n}\r\n\r\n.npi-search-input {\r\n    flex: 1;\r\n    padding: 14px;\r\n    border: 1px solid #ccc;\r\n}\r\n\r\n.npi-search-button {\r\n    padding: 14px 28px;\r\n    border: none;\r\n    background: #2c2c2c;\r\n    color: white;\r\n    cursor: pointer;\r\n}\r\n\r\n.npi-search-button:hover {\r\n    background: #000;\r\n}\r\n<\/style>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5fa6a40 e-con-full e-flex e-con e-parent\" data-id=\"5fa6a40\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-838ab04 elementor-widget elementor-widget-shortcode\" data-id=\"838ab04\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\">\n    <section\n        id=\"npid-protein-chart-785384\"\n        class=\"npid-protein-class-section\"\n        data-browse-url=\"https:\/\/npi-disruptors.com\/index.php\/browse\/\"\n    >\n        <div class=\"npid-section-header\">\n            <h2>Protein Class Distribution in NPID<\/h2>\n            <p>\n                Broad functional classification of\n                77                NPID-associated proteins based on InterPro family\/domain\n                annotations and manual curation.\n            <\/p>\n        <\/div>\n\n        <div class=\"npid-protein-class-layout\">\n\n            <div class=\"npid-chart-box\">\n                <div class=\"npid-chart-canvas-wrap\">\n                    <canvas id=\"npid-protein-chart-785384-canvas\"><\/canvas>\n                <\/div>\n\n                <div\n                    id=\"npid-protein-chart-785384-legend\"\n                    class=\"npid-custom-legend\"\n                ><\/div>\n            <\/div>\n\n            <div class=\"npid-table-box\">\n                <table class=\"npid-protein-class-table\">\n                    <thead>\n                        <tr>\n                            <th>Broad protein class<\/th>\n                            <th>Count<\/th>\n                            <th>Percentage<\/th>\n                        <\/tr>\n                    <\/thead>\n\n                    <tbody>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=RNA-binding%20\/%20RNA%20metabolism%20protein&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        RNA-binding \/ RNA metabolism protein                                    <\/a>\n                                <\/td>\n                                <td>17<\/td>\n                                <td>\n                                    22.1%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=Nuclease%20\/%20DNA-RNA%20repair%20enzyme&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        Nuclease \/ DNA-RNA repair enzyme                                    <\/a>\n                                <\/td>\n                                <td>13<\/td>\n                                <td>\n                                    16.9%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=DNA\/RNA%20polymerase%20and%20replication%20protein&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        DNA\/RNA polymerase and replication protein                                    <\/a>\n                                <\/td>\n                                <td>11<\/td>\n                                <td>\n                                    14.3%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=Viral%20replication%20\/%20viral%20nucleic-acid-related%20protein&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        Viral replication \/ viral nucleic-acid-related protein                                    <\/a>\n                                <\/td>\n                                <td>7<\/td>\n                                <td>\n                                    9.1%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=tRNA-related%20enzyme&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        tRNA-related enzyme                                    <\/a>\n                                <\/td>\n                                <td>6<\/td>\n                                <td>\n                                    7.8%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=Other%20enzyme%20\/%20miscellaneous&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        Other enzyme \/ miscellaneous                                    <\/a>\n                                <\/td>\n                                <td>6<\/td>\n                                <td>\n                                    7.8%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=Transcription%20factor%20\/%20transcription%20regulator&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        Transcription factor \/ transcription regulator                                    <\/a>\n                                <\/td>\n                                <td>5<\/td>\n                                <td>\n                                    6.5%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=Translation%20\/%20ribosomal%20protein&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        Translation \/ ribosomal protein                                    <\/a>\n                                <\/td>\n                                <td>5<\/td>\n                                <td>\n                                    6.5%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=DNA\/RNA%20modification%20or%20nucleotide%20metabolism%20enzyme&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        DNA\/RNA modification or nucleotide metabolism enzyme                                    <\/a>\n                                <\/td>\n                                <td>4<\/td>\n                                <td>\n                                    5.2%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=CRISPR-Cas%20\/%20prokaryotic%20antiviral%20defense%20protein&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        CRISPR-Cas \/ prokaryotic antiviral defense protein                                    <\/a>\n                                <\/td>\n                                <td>2<\/td>\n                                <td>\n                                    2.6%\n                                <\/td>\n                            <\/tr>\n                                                    \n                            <tr>\n                                <td>\n                                    <a\n                                        class=\"npid-class-table-link\"\n                                        href=\"https:\/\/npi-disruptors.com\/index.php\/browse\/?npi_q&#038;npi_class=Argonaute%20\/%20RNAi-related%20protein&#038;npi_organism&#038;npi_reviewed\"\n                                    >\n                                        Argonaute \/ RNAi-related protein                                    <\/a>\n                                <\/td>\n                                <td>1<\/td>\n                                <td>\n                                    1.3%\n                                <\/td>\n                            <\/tr>\n                        \n                        <tr class=\"npid-total-row\">\n                            <td>Total<\/td>\n                            <td>77<\/td>\n                            <td>100%<\/td>\n                        <\/tr>\n                    <\/tbody>\n                <\/table>\n            <\/div>\n\n        <\/div>\n    <\/section>\n\n    <style>\n 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font-size: 14px;\n            }\n\n            .npid-chart-canvas-wrap {\n                max-width: 320px;\n                height: 300px;\n            }\n\n            .npid-custom-legend {\n                grid-template-columns: 1fr;\n                font-size: 11.5px;\n            }\n        }\n    <\/style>\n\n    <script>\n    (function () {\n        const sectionId = \"npid-protein-chart-785384\";\n        const canvasId = \"npid-protein-chart-785384-canvas\";\n        const legendId = \"npid-protein-chart-785384-legend\";\n        const labels = [\"RNA-binding \\\/ RNA metabolism protein\",\"Nuclease \\\/ DNA-RNA repair enzyme\",\"DNA\\\/RNA polymerase and replication protein\",\"Viral replication \\\/ viral nucleic-acid-related protein\",\"tRNA-related enzyme\",\"Other enzyme \\\/ miscellaneous\",\"Transcription factor \\\/ transcription regulator\",\"Translation \\\/ ribosomal protein\",\"DNA\\\/RNA modification or nucleotide metabolism enzyme\",\"CRISPR-Cas \\\/ prokaryotic 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