{"id":795,"date":"2026-06-11T23:50:21","date_gmt":"2026-06-11T15:50:21","guid":{"rendered":"https:\/\/npi-disruptors.com\/index.php\/proteins\/p19838\/"},"modified":"2026-07-22T23:50:16","modified_gmt":"2026-07-22T15:50:16","slug":"p19838","status":"publish","type":"proteins","link":"https:\/\/npi-disruptors.com\/index.php\/proteins\/p19838\/","title":{"rendered":"P19838"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","class_list":["post-795","proteins","type-proteins","status-publish","hentry"],"acf":{"uniprot_id":"P19838","uniprot_related_pdbs":"8tqd","protein_pocket_json":"[{\"pdb_id\":\"8tqd\",\"pockets\":[{\"compound_name\":\"JMR\",\"ligand_instance\":\"A:JMR301\",\"pocket_id\":\"8tqd_A:JMR301\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"1svc\",\"2o61\",\"3gut\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"1svc\",\"reference_na_type\":\"DNA-bound\",\"reference_na_description\":\"DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3')\",\"source_pocket_residue_count\":4,\"source_pocket_residue_set\":\"A:ARG56;A:CYS61;A:GLU62;A:TYR59\",\"source_hydrophobic_ratio\":0.0,\"source_positive_ratio\":0.25,\"mapped_uniprot_position_count\":4,\"reference_pocket_residue_count\":4,\"reference_pocket_residue_set\":\"P:ALA62;P:ARG57;P:GLU63;P:TYR60\",\"reference_hydrophobic_ratio\":0.25,\"reference_positive_ratio\":0.25,\"source_alignment_chain\":\"A\",\"reference_alignment_chain\":\"P\",\"global_rmsd_A\":1.68,\"global_ca_count\":198,\"pocket_rmsd_A\":0.6203,\"pocket_ca_count\":4,\"sequence_identity\":0.9949,\"overlay_cif_file\":\"8tqd__1svc__src-A__ref-P__JMR__A_JMR301__8tqd_A_JMR301__overlay.cif\",\"overlay_cif_url\":\"https:\/\/npi-disruptors-structures.s3.us-east-2.amazonaws.com\/aligned_reference_cif\/8tqd__1svc__src-A__ref-P__JMR__A_JMR301__8tqd_A_JMR301__overlay.cif\"},{\"compound_name\":\"JMR\",\"ligand_instance\":\"A:JMR301\",\"pocket_id\":\"8tqd_A:JMR301\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"1svc\",\"2o61\",\"3gut\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"2o61\",\"reference_na_type\":\"DNA-bound\",\"reference_na_description\":\"36-MER; 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