{"id":806,"date":"2026-06-11T23:50:26","date_gmt":"2026-06-11T15:50:26","guid":{"rendered":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q06078\/"},"modified":"2026-07-22T23:50:19","modified_gmt":"2026-07-22T15:50:19","slug":"q06078","status":"publish","type":"proteins","link":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q06078\/","title":{"rendered":"Q06078"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","class_list":["post-806","proteins","type-proteins","status-publish","hentry"],"acf":{"uniprot_id":"Q06078","uniprot_related_pdbs":"4nsx","protein_pocket_json":"[{\"pdb_id\":\"4nsx\",\"pockets\":[{\"compound_name\":\"FLC\",\"ligand_instance\":\"A:FLC701\",\"pocket_id\":\"4nsx_A:FLC701\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"6zqc\",\"7suk\",\"9g33\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"6zqc\",\"reference_na_type\":\"RNA-bound\",\"reference_na_description\":\"5ETS RNA; 18S rRNA; U3 snoRNA\",\"source_pocket_residue_count\":9,\"source_pocket_residue_set\":\"A:ARG103;A:GLY104;A:HIS88;A:ILE60;A:LYS102;A:PHE70;A:TYR49;A:TYR89;A:VAL90\",\"source_hydrophobic_ratio\":0.3333,\"source_positive_ratio\":0.3333,\"mapped_uniprot_position_count\":9,\"reference_pocket_residue_count\":9,\"reference_pocket_residue_set\":\"UU:ARG103;UU:GLY104;UU:HIS88;UU:ILE60;UU:LYS102;UU:PHE70;UU:TYR49;UU:TYR89;UU:VAL90\",\"reference_hydrophobic_ratio\":0.3333,\"reference_positive_ratio\":0.3333,\"source_alignment_chain\":\"A\",\"reference_alignment_chain\":\"UU\",\"global_rmsd_A\":7.2246,\"global_ca_count\":634,\"pocket_rmsd_A\":0.3179,\"pocket_ca_count\":9,\"sequence_identity\":0.9874,\"overlay_cif_file\":\"4nsx__6zqc__src-A__ref-UU__FLC__A_FLC701__4nsx_A_FLC701__overlay.cif\",\"overlay_cif_url\":\"https:\/\/npi-disruptors-structures.s3.us-east-2.amazonaws.com\/aligned_reference_cif\/4nsx__6zqc__src-A__ref-UU__FLC__A_FLC701__4nsx_A_FLC701__overlay.cif\"},{\"compound_name\":\"FLC\",\"ligand_instance\":\"A:FLC701\",\"pocket_id\":\"4nsx_A:FLC701\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"6zqc\",\"7suk\",\"9g33\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"7suk\",\"reference_na_type\":\"RNA-bound\",\"reference_na_description\":\"5' ETS; 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