{"id":811,"date":"2026-06-11T23:50:29","date_gmt":"2026-06-11T15:50:29","guid":{"rendered":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q5vys8\/"},"modified":"2026-07-22T23:50:21","modified_gmt":"2026-07-22T15:50:21","slug":"q5vys8","status":"publish","type":"proteins","link":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q5vys8\/","title":{"rendered":"Q5VYS8"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","class_list":["post-811","proteins","type-proteins","status-publish","hentry"],"acf":{"uniprot_id":"Q5VYS8","uniprot_related_pdbs":"5w0n","protein_pocket_json":"[{\"pdb_id\":\"5w0n\",\"pockets\":[{\"compound_name\":\"UPU\",\"ligand_instance\":\"A:UPU1403\",\"pocket_id\":\"5w0n_A:UPU1403\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"5w0m\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"5w0m\",\"reference_na_type\":\"RNA-bound\",\"reference_na_description\":\"U5 single-stranded RNA\",\"source_pocket_residue_count\":20,\"source_pocket_residue_set\":\"A:ALA1102;A:ALA1127;A:ALA1163;A:ASN1124;A:ASP1058;A:ASP1060;A:ASP1119;A:GLY1354;A:HIS1286;A:HIS1355;A:ILE1099;A:ILE1106;A:ILE1353;A:LYS1103;A:LYS1352;A:PHE1045;A:SER1121;A:SER1164;A:THR1101;A:VAL1104\",\"source_hydrophobic_ratio\":0.4,\"source_positive_ratio\":0.2,\"mapped_uniprot_position_count\":20,\"reference_pocket_residue_count\":56,\"reference_pocket_residue_set\":\"A:ALA1060;A:ALA1102;A:ALA1127;A:ALA1163;A:ASN1124;A:ASP1058;A:ASP1119;A:GLY1354;A:HIS1286;A:HIS1355;A:ILE1099;A:ILE1106;A:ILE1353;A:LYS1103;A:LYS1352;A:PHE1045;A:SER1121;A:SER1164;A:THR1101;A:VAL1104;B:ALA1060;B:ALA1102;B:ALA1127;B:ALA1163;B:ASN1124;B:ASP1058;B:ASP1119;B:HIS1286;B:ILE1099;B:ILE1106;B:LYS1103;B:PHE1045;B:SER1121;B:SER1164;B:THR1101;B:VAL1104;C:ALA1060;C:ALA1102;C:ALA1127;C:ALA1163;C:ASN1124;C:ASP1058;C:ASP1119;C:GLY1354;C:HIS1286;C:HIS1355;C:ILE1099;C:ILE1106;C:ILE1353;C:LYS1103;C:LYS1352;C:PHE1045;C:SER1121;C:SER1164;C:THR1101;C:VAL1104\",\"reference_hydrophobic_ratio\":0.4643,\"reference_positive_ratio\":0.1786,\"source_alignment_chain\":\"A\",\"reference_alignment_chain\":\"A\",\"global_rmsd_A\":0.2172,\"global_ca_count\":372,\"pocket_rmsd_A\":0.1848,\"pocket_ca_count\":20,\"sequence_identity\":0.9973,\"overlay_cif_file\":\"5w0n__5w0m__src-A__ref-A__UPU__A_UPU1403__5w0n_A_UPU1403__overlay.cif\",\"overlay_cif_url\":\"https:\/\/npi-disruptors-structures.s3.us-east-2.amazonaws.com\/aligned_reference_cif\/5w0n__5w0m__src-A__ref-A__UPU__A_UPU1403__5w0n_A_UPU1403__overlay.cif\"}]}]","protein_name":"Terminal uridylyltransferase 7","protein_synonyms":"Zinc finger CCHC domain-containing protein 6; TUTase 7","gene_name":"TUT7","gene_synonyms":"HS2; KIAA1711; ZCCHC6","organism_name":"Homo sapiens","uniprot_reviewed":"Reviewed","interpro_family":"","interpro_domains":"IPR001878: Zinc finger, CCHC-type; IPR002058: PAP\/25A-associated; IPR003604: Matrin\/U1-C-like, C2H2-type zinc finger; IPR045100: Terminal uridylyltransferase 4\/7, nucleotidyltransferase domain; IPR054708: Poly(A) RNA polymerase, mitochondrial-like, central palm domain","interpro_homologous_superfamily":"IPR036875: Zinc finger, CCHC-type superfamily; IPR043519: Nucleotidyltransferase superfamily","pfam_domains":"","interpro_other_entries":"","broad_protein_class":"DNA\/RNA polymerase and replication protein","gpt_checked_class":"RNA-binding \/ RNA metabolism protein","broad_class_reason":"matched keywords: nucleotidyltransferase, polymerase, rna polymerase","all_matched_classes":"DNA\/RNA polymerase and replication protein [nucleotidyltransferase, polymerase, rna polymerase]"},"_links":{"self":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins\/811","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins"}],"about":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/types\/proteins"}],"wp:attachment":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/media?parent=811"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}