{"id":812,"date":"2026-06-11T23:50:29","date_gmt":"2026-06-11T15:50:29","guid":{"rendered":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q5y812\/"},"modified":"2026-07-22T23:50:21","modified_gmt":"2026-07-22T15:50:21","slug":"q5y812","status":"publish","type":"proteins","link":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q5y812\/","title":{"rendered":"Q5Y812"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","class_list":["post-812","proteins","type-proteins","status-publish","hentry"],"acf":{"uniprot_id":"Q5Y812","uniprot_related_pdbs":"5ffz","protein_pocket_json":"[{\"pdb_id\":\"5ffz\",\"pockets\":[{\"compound_name\":\"ET\",\"ligand_instance\":\"A:ET301\",\"pocket_id\":\"5ffz_A:ET301\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"5fb2\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"5fb2\",\"reference_na_type\":\"DNA-bound\",\"reference_na_description\":\"DNA (5'-D(*CP*GP*TP*TP*A)-3')\",\"source_pocket_residue_count\":5,\"source_pocket_residue_set\":\"A:ASN31;A:GLY34;A:GLY38;A:HIS35;A:PHE104\",\"source_hydrophobic_ratio\":0.2,\"source_positive_ratio\":0.2,\"mapped_uniprot_position_count\":5,\"reference_pocket_residue_count\":5,\"reference_pocket_residue_set\":\"A:ASN31;A:GLY34;A:GLY38;A:HIS35;A:PHE104\",\"reference_hydrophobic_ratio\":0.2,\"reference_positive_ratio\":0.2,\"source_alignment_chain\":\"A\",\"reference_alignment_chain\":\"A\",\"global_rmsd_A\":4.0511,\"global_ca_count\":138,\"pocket_rmsd_A\":0.236,\"pocket_ca_count\":5,\"sequence_identity\":0.9928,\"overlay_cif_file\":\"5ffz__5fb2__src-A__ref-A__ET__A_ET301__5ffz_A_ET301__overlay.cif\",\"overlay_cif_url\":\"https:\/\/npi-disruptors-structures.s3.us-east-2.amazonaws.com\/aligned_reference_cif\/5ffz__5fb2__src-A__ref-A__ET__A_ET301__5ffz_A_ET301__overlay.cif\"}]}]","protein_name":"MarR family regulatory protein","protein_synonyms":"","gene_name":"mepR","gene_synonyms":"ACR79_09305; BN1321_80052; CNH36_01895; DQU50_09355; E1948_01710; E1948_06500; EIG94_00835; EIH03_04040; EP54_02880; EQ90_08705; ERS391062_01871; G0Z31_05155; G6Y24_06545; GF599_06325; GO793_15615; GO814_10745; GO941_13505; GO942_09445; GQX37_11080; GQX52_00855; GZ130_07485; GZ164_04595; H2649_05255; LB359_03350; M1K003_0421; NCTC10702_00659; NCTC13131_05788; NCTC5664_00388; NCTC7878_00347; NCTC7972_01611; NCTC8317_00285; SAMEA1029512_01461; SAMEA1029528_01243; SAMEA1466929_01741; SAMEA1531725_01811; SAMEA2078260_01697; SAMEA2078588_01240; SAMEA2080344_01299; SAMEA2081063_00451; SAMEA4008575_01717; SAMEA4552975_01438; SAMEA70146418_01252; SAMEA70153168_00678","organism_name":"Staphylococcus aureus","uniprot_reviewed":"Unreviewed","interpro_family":"","interpro_domains":"IPR000835: MarR-type HTH domain","interpro_homologous_superfamily":"IPR036388: Winged helix-like DNA-binding domain superfamily; IPR036390: Winged helix DNA-binding domain superfamily","pfam_domains":"","interpro_other_entries":"","broad_protein_class":"Transcription factor \/ transcription regulator","gpt_checked_class":"Transcription factor \/ transcription regulator","broad_class_reason":"No rule matched","all_matched_classes":"Transcription factor \/ transcription regulator"},"_links":{"self":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins\/812","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins"}],"about":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/types\/proteins"}],"wp:attachment":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/media?parent=812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}