{"id":820,"date":"2026-06-11T23:50:33","date_gmt":"2026-06-11T15:50:33","guid":{"rendered":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q96li5\/"},"modified":"2026-07-22T23:50:23","modified_gmt":"2026-07-22T15:50:23","slug":"q96li5","status":"publish","type":"proteins","link":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q96li5\/","title":{"rendered":"Q96LI5"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","class_list":["post-820","proteins","type-proteins","status-publish","hentry"],"acf":{"uniprot_id":"Q96LI5","uniprot_related_pdbs":"3ngq","protein_pocket_json":"[{\"pdb_id\":\"3ngq\",\"pockets\":[{\"compound_name\":\"1PS\",\"ligand_instance\":\"A:1PS556\",\"pocket_id\":\"3ngq_A:1PS556\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"3ngo\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"3ngo\",\"reference_na_type\":\"DNA-bound\",\"reference_na_description\":\"5'-D(*AP*AP*AP*A)-3'\",\"source_pocket_residue_count\":7,\"source_pocket_residue_set\":\"A:ASN412;A:ASN479;A:LEU414;A:LYS371;A:PHE484;A:PRO365;A:TRP363\",\"source_hydrophobic_ratio\":0.5714,\"source_positive_ratio\":0.1429,\"mapped_uniprot_position_count\":7,\"reference_pocket_residue_count\":7,\"reference_pocket_residue_set\":\"A:ASN412;A:ASN479;A:LEU414;A:LYS371;A:PHE484;A:PRO365;A:TRP363\",\"reference_hydrophobic_ratio\":0.5714,\"reference_positive_ratio\":0.1429,\"source_alignment_chain\":\"A\",\"reference_alignment_chain\":\"A\",\"global_rmsd_A\":0.4198,\"global_ca_count\":331,\"pocket_rmsd_A\":0.2056,\"pocket_ca_count\":7,\"sequence_identity\":0.997,\"overlay_cif_file\":\"3ngq__3ngo__src-A__ref-A__1PS__A_1PS556__3ngq_A_1PS556__overlay.cif\",\"overlay_cif_url\":\"https:\/\/npi-disruptors-structures.s3.us-east-2.amazonaws.com\/aligned_reference_cif\/3ngq__3ngo__src-A__ref-A__1PS__A_1PS556__3ngq_A_1PS556__overlay.cif\"}]}]","protein_name":"CCR4-NOT transcription complex subunit 6-like","protein_synonyms":"Carbon catabolite repressor protein 4 homolog B","gene_name":"CNOT6L","gene_synonyms":"CCR4B","organism_name":"Homo sapiens","uniprot_reviewed":"Reviewed","interpro_family":"IPR050410: CCR4\/nocturin mRNA turnover and transcription","interpro_domains":"IPR005135: Endonuclease\/exonuclease\/phosphatase; IPR034967: CCR4-NOT transcription complex subunit 6-like","interpro_homologous_superfamily":"IPR032675: Leucine-rich repeat domain superfamily; IPR036691: Endonuclease\/exonuclease\/phosphatase superfamily","pfam_domains":"","interpro_other_entries":"IPR001611: Leucine-rich repeat; IPR003591: Leucine-rich repeat, typical subtype","broad_protein_class":"Nuclease \/ DNA-RNA repair enzyme","gpt_checked_class":"RNA-binding \/ RNA metabolism protein","broad_class_reason":"matched keywords: endonuclease, exonuclease, nuclease","all_matched_classes":"Nuclease \/ DNA-RNA repair enzyme [endonuclease, exonuclease, nuclease] || RNA-binding \/ RNA metabolism protein [ccr4, mrna turnover, nocturin, rna turnover]"},"_links":{"self":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins\/820","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins"}],"about":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/types\/proteins"}],"wp:attachment":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/media?parent=820"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}