{"id":833,"date":"2026-06-11T23:50:38","date_gmt":"2026-06-11T15:50:38","guid":{"rendered":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q9vaa9\/"},"modified":"2026-07-22T23:50:27","modified_gmt":"2026-07-22T15:50:27","slug":"q9vaa9","status":"publish","type":"proteins","link":"https:\/\/npi-disruptors.com\/index.php\/proteins\/q9vaa9\/","title":{"rendered":"Q9VAA9"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","class_list":["post-833","proteins","type-proteins","status-publish","hentry"],"acf":{"uniprot_id":"Q9VAA9","uniprot_related_pdbs":"6kcu","protein_pocket_json":"[{\"pdb_id\":\"6kcu\",\"pockets\":[{\"compound_name\":\"BTB\",\"ligand_instance\":\"A:BTB800\",\"pocket_id\":\"6kcu_A:BTB800\",\"cutoff_A\":4.0,\"na_match_pdb_ids\":[\"6kco\"],\"na_contributing_pdb_ids\":[],\"reference_pdb_id\":\"6kco\",\"reference_na_type\":\"DNA-bound\",\"reference_na_description\":\"DNA (5'-D(*TP*CP*CP*CP*T)-3')\",\"source_pocket_residue_count\":8,\"source_pocket_residue_set\":\"A:ALA50;A:GLU48;A:PHE43;A:THR46;A:THR49;A:TRP26;A:TYR23;A:VAL20\",\"source_hydrophobic_ratio\":0.5,\"source_positive_ratio\":0.0,\"mapped_uniprot_position_count\":8,\"reference_pocket_residue_count\":127,\"reference_pocket_residue_set\":\"A:ALA50;A:GLU48;A:PHE43;A:THR46;A:THR49;A:TRP26;A:TYR23;A:VAL20;B:ALA50;B:GLU48;B:PHE43;B:THR46;B:THR49;B:TRP26;B:TYR23;B:VAL20;C:ALA50;C:GLU48;C:PHE43;C:THR46;C:THR49;C:TRP26;C:TYR23;C:VAL20;D:ALA50;D:GLU48;D:PHE43;D:THR46;D:THR49;D:TRP26;D:TYR23;D:VAL20;E:ALA50;E:GLU48;E:PHE43;E:THR46;E:THR49;E:TRP26;E:TYR23;E:VAL20;F:ALA50;F:GLU48;F:PHE43;F:THR46;F:THR49;F:TRP26;F:TYR23;F:VAL20;G:ALA50;G:GLU48;G:PHE43;G:THR46;G:THR49;G:TRP26;G:TYR23;G:VAL20;H:ALA50;H:GLU48;H:PHE43;H:THR46;H:THR49;H:TRP26;H:TYR23;H:VAL20;I:ALA50;I:GLU48;I:PHE43;I:THR46;I:THR49;I:TRP26;I:TYR23;I:VAL20;J:ALA50;J:GLU48;J:PHE43;J:THR46;J:THR49;J:TRP26;J:TYR23;J:VAL20;K:ALA50;K:GLU48;K:PHE43;K:THR46;K:THR49;K:TRP26;K:TYR23;K:VAL20;L:ALA50;L:GLU48;L:PHE43;L:THR46;L:THR49;L:TRP26;L:TYR23;L:VAL20;M:ALA50;M:GLU48;M:PHE43;M:THR46;M:THR49;M:TRP26;M:TYR23;M:VAL20;N:ALA50;N:GLU48;N:PHE43;N:THR46;N:THR49;N:TRP26;N:TYR23;N:VAL20;O:ALA50;O:GLU48;O:PHE43;O:THR46;O:THR49;O:TRP26;O:TYR23;O:VAL20;P:GLU48;P:PHE43;P:THR46;P:THR49;P:TRP26;P:TYR23;P:VAL20\",\"reference_hydrophobic_ratio\":0.4961,\"reference_positive_ratio\":0.0,\"source_alignment_chain\":\"A\",\"reference_alignment_chain\":\"A\",\"global_rmsd_A\":11.4592,\"global_ca_count\":83,\"pocket_rmsd_A\":0.3958,\"pocket_ca_count\":8,\"sequence_identity\":1.0,\"overlay_cif_file\":\"6kcu__6kco__src-A__ref-A__BTB__A_BTB800__6kcu_A_BTB800__overlay.cif\",\"overlay_cif_url\":\"https:\/\/npi-disruptors-structures.s3.us-east-2.amazonaws.com\/aligned_reference_cif\/6kcu__6kco__src-A__ref-A__BTB__A_BTB800__6kcu_A_BTB800__overlay.cif\"}]}]","protein_name":"JIL-1 anchoring and stabilizing protein, isoform A","protein_synonyms":"","gene_name":"Jasper","gene_synonyms":"DmelCG7946; dP75; JASPer; CG7946; Dmel_CG7946","organism_name":"Drosophila melanogaster","uniprot_reviewed":"Unreviewed","interpro_family":"","interpro_domains":"IPR000313: PWWP domain; IPR021567: Lens epithelium-derived growth factor, integrase-binding domain","interpro_homologous_superfamily":"IPR035441: TFIIS\/LEDGF domain superfamily; IPR036218: HIV integrase-binding domain superfamily","pfam_domains":"","interpro_other_entries":"","broad_protein_class":"Transcription factor \/ transcription regulator","gpt_checked_class":"Transcription factor \/ transcription regulator","broad_class_reason":"No rule matched","all_matched_classes":"Transcription factor \/ transcription regulator"},"_links":{"self":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins\/833","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/proteins"}],"about":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/types\/proteins"}],"wp:attachment":[{"href":"https:\/\/npi-disruptors.com\/index.php\/wp-json\/wp\/v2\/media?parent=833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}